Novel compounds

A compound of the formula:

• wherein
• R1 is an optionally substituted aryl or an optionally substituted heteroaryl ring;
• R2 and R2′ are independently selected from hydrogen, C1-10 alkyl, C3-7cycloalkyl, C3-7cycloalkylC1-10alkyl, C5-7 cycloalkenyl, C5-7 cycloalkenyl-C1-10alkyl, aryl, arylC1-10 alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic, or a heterocyclylC1-10 alkyl moiety, wherein all of the moieties are optionally substituted, or R2 and R2′ together with the nitrogen to which they are attached form a 5 to 7 membered optionally substituted ring, which ring may contain an additional heteroatom selected from O/N/S;
• Ra is hydrogen, or an optionally substituted C1-4 alkyl;
• Rg is selected from an optionally substituted C1-10 alkyl, —CH2—CH2—O—CH2—CH2—, —CH2—C(O)—CH2, CH2—C(O)N(R12)CH2—CH2—, CH2—N(R12)C(O)CH2—, CH2—CH(OR12)—CH2, CH2—C(O)O—CH2—CH2, or CH2—CH2—O—C(O)CH2—;
• R12 is hydrogen, or an optionally substituted C1-4 alkyl;
• R3 is a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkylC1-4alkyl, aryl, arylC1-10 alkyl, heteroaryl, heteroarylC1-10 alkyl, heterocyclic, or a heterocyclylc 1-10 alkyl moiety, which moieties are all optionally substituted;
• and a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof.