Treatment of anhedonia
AssigneeSilvan S. Tomkins Institute, Inc.
InventorsDonald Nathanson, Marc Samet
Life of this patent
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Abstract
A therapeutic method for the enhancement of mood in patients afflicted with iatrogenic anhedonia secondary to chronic increases in the availability and/or efficiency of serotonin, with or without increases in the availability and/or efficiency of norepinephrine.
Claims21
A method of treatment comprising the steps of:
- a. identifying iatrogenic anhedonia in a patient being treated with a first pharmaceutical agent that increases serotonin;
- and
- b. increasing dopaminergic activity in the patient by administrating a second pharmaceutical agent in an amount effective to ameliorate the iatrogenic anhedonia.
A method for the treatment of iatrogenic anhedonia in a patient currently being treated for depression by administration of a first pharmaceutical agent known to increase the availability or efficiency of serotonin, the method comprising the steps of:
- a. continuing the treatment of the patient with the first pharmaceutical agent known to increase the availability or efficiency of serotonin;
- and
- b. increasing dopaminergic activity in the patient by administering a second pharmaceutical agent in an amount effective to ameliorate the iatrogenic anhedonia.
A method for the treatment of iatrogenic anhedonia comprising the steps of:
- a. identifying a patient having iatrogenic anhedonia;
- b. treating the patient with a pharmaceutical agent that enhances dopaminergic availability or efficiency;
- c. modulating doses of the pharmaceutical agent that enhances dopaminergic availability or efficiency based upon clinical presentation and therapeutic responses in the patient.
A method of treatment comprising the steps of:
- a. identification of iatrogenic anhedonia in a patient who had been treated with a first pharmaceutical agent that increases serotonin efficiency;
- and
- b. increasing dopaminergic activity in the patient by administering a second pharmaceutical agent in an amount effective to ameliorate the iatrogenic anhedonia.
The method of clam 13, wherein the patient had been treated with the first pharmaceutical agent for a period of about 6 months.
Dependencies are inferred from the claim text.