Back to results
US 2006/0217320 A1Published application
Soft gel formulations for saquinavir
AssigneeCristalia Productos Quimicos Farmaceuticos Ltda
InventorsOgari Pacheco, Elisa Russo, Valter Russo
Life of this patent
Estimating the term…
Abstract
The present invention describes a pharmaceutical composition with increased bioavailability, which is suitable for preparing microcapsules for the therapeutic administration of a protease inhibitor. It is also described a process for preparing a pharmaceutical composition with increased bioavailability, suitable to prepare concentrate pharmaceutical compositions comprising retroviral protease inhibitors.
Claims33
1-36. (canceled)
A pharmaceutical composition for oral administration of saquinavir comprising:
- (i) saquinavir or its pharmaceutical acceptable salts as the active ingredient in a concentration ranging from 10% to 80% in weight of the final composition;
- (ii) a long chain fatty acid of C12-18 in a concentration ranging from 20% to 80% in weight of the final composition;
- (iii) at least an alcohol of chain C2-4 in a concentration ranging from 2% to 20% in weight of the final composition;
- (iv) a non-ionic surfactant in a concentration ranging from 0.1% to 30% in weight of the final composition;
- (v) a pharmaceutical acceptable antioxidant in a concentration ranging from 0.001% to 2.0% in weight of the final composition.
2 more elements
Dependencies are inferred from the claim text.