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US 2006/0217309 A1Published application
Novel cyclosporine analog formulations
AssigneeIsotechnika Inc., a Canada corporation
InventorsSelvaraj Naicker, Randall Yatscoff, Robert Foster
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Abstract
The present invention relates to formulations containing cyclosporin analogs that are structurally similar to cyclosporin A, in particular isomeric mixtures of cyclosporin analogs that are structurally similar to cyclosporin A. The formulations form stable microemulsion preconcentrates and may provide superior drug bioavailability and/or may reduce one or more adverse effects associated with the administration of cyclosporin. Also disclosed are methods for using and preparing the formulations.
Claims34
1-45. (canceled)
A pharmaceutical composition comprising:
- a) a pharmaceutically effective amount of ISATx247;
- b) Vitamin E TPGS;
- c) MCT oil;
- d) an emulsifier;
- and
- e) ethanol
3 more elements
Dependencies are inferred from the claim text.