US 2006/0217303 A1 · Compounds and Methods for Treating Seizure Disorders

Abstract

This invention provides methods for alleviating seizure disorders in an animal, particularly epilepsy, by regulating the flux through the gluconeogenic enzyme PEPCK in brain cells.

Claims41

Dependent claims

A method for reducing epileptic bursting in brain cells, the method comprising the step of contacting the cells with an effective amount of a compound that regulates the rate of flux through phosphoenolpyruvate carboxykinase (PEPCK).

Dependencies are inferred from the claim text.

Facts

Application

11/277,457Filed 24 Mar 2006

Priority

25 Mar 2005

Published

28 Sep 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

A61K 31/45
Non condensed piperidines, e.g. piperocaine: having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
A61K 31/19
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids: carboxylic acids, e.g. valproic acid
A61K 31/202
Having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids: having three or more double…
A61K 31/203
Having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids: retinoic acids ; Salts thereof

Abstract

This invention provides methods for alleviating seizure disorders in an animal, particularly epilepsy, by regulating the flux through the gluconeogenic enzyme PEPCK in brain cells.

Claims41

Dependent claims

Dependencies are inferred from the claim text.

Compounds and Methods for Treating Seizure Disorders

Life of this patent

Abstract

Claims41

Compounds and Methods for Treating Seizure Disorders

Life of this patent

Abstract

Claims41