Prion decontamination
OwnerGraham Jackson, John Collinge +1inventors
InventorsGraham Jackson, John Collinge, Anthony Clarke
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Abstract
The present invention relates to methods for prion decontamination comprising (i) contacting an entity to be decontaminated with a detergent, (ii) contacting said entity with one or more protease(s), and optionally (iii) autoclaving said entity. The invention further relates to kits comprising detergents and proteases for prion decontamination, and compositions comprising detergents and proteases for prion decontamination.
Claims27
A method for prion decontamination of an entity comprising (i) contacting said entity with a detergent, (ii) contacting said entity with a protease, and optionally (iii) autoclaving said entity.
A method according to claim I wherein the protease is selected from a group consisting of protease and peptidase enzymes belonging to class E. C. 3.4.-.- as defined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
A method for prion decontamination comprising (i) contacting an entity to be decontaminated with a detergent, (ii) contacting said entity with a first protease, (iii) contacting said entity with a second protease, and optionally (iv) autoclaving said entity.
A kit comprising detergent and a protease selected from the group consisting of ProteinaseK, papain, pronase, and bromelain.
A composition comprising an ionic detergent and one or more proteases selected from the group consisting of ProteinaseK, papain, pronase, and bromelain.
Dependencies are inferred from the claim text.