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US 2006/0216773 A1Published application
Method for determining the glucose concentration by fluorescence polarization
AssigneeRoche Diagnostics Operations, Inc.
InventorsJoachim Hoenes, Herbert von der Eltz
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Abstract
The invention generally relates to a method for in vivo glucose monitoring in which the glucose concentration is measured by means of fluorescence polarization by detecting the change in viscosity, caused by changes in the glucose concentration.
Claims18
A method for in vivo glucose monitoring in an individual, the method comprising:
- filling a container that is permeable to glucose and having an inner space with a mixture containing a glucose-binding lectin and a probe;
- sealing the container;
- operatively coupling the container with a sensor, wherein the sensor is for measuring the fluorescence polarization;
- implanting the container and the operatively coupled sensor into the individual;
- and
- measuring the glucose concentration by detecting a change in viscosity in the inner space of the container by means of fluorescence polarization.
3 more elements
A system for in vivo glucose monitoring in an individual using florescence polarization, the system comprising:
- a container comprising a glucose-binding lectin, and a probe;
- and
- a sensor operatively coupled to the container for measuring the glucose concentration using florescence polarization.
Dependencies are inferred from the claim text.