Insulin-like growth factor binding protein

A DNA encoding a protein or a polypeptide selected from the group consisting of:

• an insulin-like growth factor binding protein, which comprises the amino acid sequence represented by SEQ ID NO:
• 2;
• a protein comprising an amino acid sequence, wherein one or more amino acids have been deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO:
• 2, which protein substantially has an identical activity as the insulin-like growth factor binding protein;
• a protein comprising an amino acid sequence with 60% or higher identity with the amino acid sequence represented by SEQ ID NO:
• 2, wherein the protein substantially has an identical activity as the insulin-like growth factor binding protein;
• a protein comprising an amino acid sequence that includes the 75th to the 82nd amino acid residues of the amino acid sequence represented by SEQ ID NO:
• 2, wherein the protein substantially has an identical activity as the insulin-like growth factor binding protein;
• a protein comprising a partial amino acid sequence that includes the 171st to the 197th amino acid residues of the amino acid sequence represented by SEQ ID NO:
• 2, wherein the protein substantially has an identical activity as the insulin-like growth factor binding protein;
• a polypeptide comprising an amino acid sequence that includes at least 5 or more continuous amino acids in the amino acid sequence represented by SEQ ID NO:
• 2;
• and
• a polypeptide comprising an amino acid sequence that includes at least 5 or more continuous amino acids of the 171st to the 197th amino acid residues in the amino acid sequence represented by SEQ ID NO:
• 2.