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AssigneeIntercell AG
InventorsMichael Buschle, Andre Habel, Christoph Klade, Frank Mattner, Oleksandr Otava, Oresta Vytvytska, Wolfgang Zauner, Sandra Zinke, Helen Kirlappos
Estimating the term…
Described is a method for isolating Hepatitis C Virus peptides (HPs) which have a binding capacity to a MHC/HLA molecule or a complex comprising said HCV-peptide and said MHC/HLA molecule characterized by the following steps: —providing a pool of HCV-peptide, said pool containing HCV-peptides which bind to said MHC/HLA molecule and HCV-peptides which do not bind to said MHC/HLA molecule, —contacting said MHC/HLA molecule with said pool of HCV-peptides whereby a HCV-peptide which has a binding capacity to said MHC/HLA molecule binds to said MHC/HLA molecule and a complex comprising said HCV-peptide and said MHC/HLA molecule is formed, —detecting and optionally separating said complex from the HCV-peptide which do not bind to said MHC/HLA molecule and optionally isolating and characterising the HCV-peptide from said complex.
1-28. (canceled)
A method for isolating Hepatitis C Virus peptides (HPs) or isolating HCV T cell epitopes which have a binding capacity to a MHC/HLA molecule or a complex comprising the HCV-peptide or HCV T cell epitope and the MHC/HLA molecule, the method comprising:
Dependencies are inferred from the claim text.