Detection of antibacterial activity in excretory secretory product of adult trichuris suis
AssigneeBoard of Trustees of Michigan State University
InventorsLinda Mansfield, Sheila Abner
Life of this patent
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Abstract
The present invention provides a heat-stable and protease-resistant antibacterial activity in excretory-secretory products (ESP) of Trichuris suis. The antibacterial activity is not more than 10,000 MW; is resistant to boiling, trypsin, and pronase E; has a bactericidal mode of action; and is effective against Gram positive and Gram negative bacteria, including Escherichia coli, Campylobacter jejuni, Campylobacter coli, and Staphylococcus aureus. The antibacterial activity is useful in applications for killing or inhibiting the growth of microorganisms, in particular bacteria.
Claims8
1-10. (canceled)
A method for inhibiting a microorganism which comprises:
- contacting the microorganism with an excretory-secretory product of Trichuris suis which comprises at least one antibacterial activity which inhibits the growth of Campylobacter jejuni as an assay strain in a growth medium and which is resistant to boiling, freeze-thawing, trypsin, and pronase E in an amount which inhibits the microorganism.
17-29. (canceled)
Dependencies are inferred from the claim text.