Methods related to the treatment of mucosal associated conditions
OwnerRichard Miller, David Mainventors
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Abstract
Using interrupted delivery of IRMs by intermittently applying an IRM to a mucosal surface it is possible to achieve therapeutic levels and durations of cytokine induction, while substantially reducing irritation side effects.
Claims25
A method of delivering an immune response modifier (IRM) compound to a mucosal surface so as to achieve immunomodulation with reduced irritation, comprising:
- interrupted delivery of an IRM compound other than imiquimod by intermittently applying the IRM to the mucosal surface and, after each application, removing from the mucosal surface a substantial amount of the IRM at a time before it would otherwise be naturally absorbed or eliminated.
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A method of treating a condition associated with a mucosal surface with an immune response modifier (IRM) compound and reducing irritation caused by the IRM, comprising:
- interrupted delivery of an IRM other than imiquimod by intermittently applying the IRM to the affected mucosal surface for a time sufficient to achieve therapeutic immunomodulation and, after each application, removing from the mucosal surface a substantial amount of the IRM at a time before it would otherwise be naturally absorbed or eliminated.
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Dependencies are inferred from the claim text.