Hypoallergenic allergy vaccines based on the timothy grass pollen allergen phl p7
AssigneeBIOMAY Produktions- und Handels-Aktiengesellschaft
InventorsKerstin Westritschnig, Margarete Focke, Anna Twardosz, Peter Valent, Petra Verdino, Walter Keller, Dietrich Kraft, Rudolf Valenta
Life of this patent
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Abstract
The present invention pertains to polypeptides derived from the timothy grass pollen allergen Phi p 7. The polypeptides display reduced allergen activity and are useful as allergy vaccines for treatment of sensitized allergic patients and for prophylactic vaccination.
Claims15
A mutated polypeptide derived from the pollen allergen Phi p 7, said polypeptide selected from the group consisting of the sequences as shown in SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, and SEQ ID NO:6, whereby said polypeptide has a reduced allergenic activity compared to wild type Phi p 7.
9-13. (canceled)
Dependencies are inferred from the claim text.