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US 2006/0216299 A1Published application
Cell cycle targets and peptides
AssigneeRigel Pharmaceuticals, Inc.
InventorsYasumichi Hitoshi, David Anderson
Life of this patent
Estimating the term…
Abstract
The present invention relates to regulation of cellular proliferation. More particularly, the present invention binding partners of peptides that block the cell cycle. These binding partners are targets for drug discovery, e.g., for small molecule cancer therapeutics.
Claims37
A method for identifying a compound that modulates cellular proliferation, the method comprising the steps of:
- (i) contacting the compound with a peptide 35, 38, 40, or 41 binding partner;
- and
- (ii) determining the functional effect of the compound upon the binding partner polypeptide.
A peptide comprising peptide 35, 38, 40, or 41.
Dependencies are inferred from the claim text.