TNFalpha-neutralizing antibodies
AssigneeEpitomics, Inc.
InventorsFernando Couto, Kristin Hendricks, Stacey Wallace
Life of this patent
Estimating the term…
Abstract
The invention provides monoclonal antibodies that neutralize TNα activity. The monoclonal antibodies may be rabbit monoclonal antibodies or monoclonal antibodies having CDR regions derived from those rabbit monoclonal antibodies. In certain embodiments, the monoclonal antibodies may be humanized. Methods of using the subject antibodies to inhibit TNFα activity, methods of treatment using those antibodies and kits containing the same are also provided. The invention finds use in a variety of research and medical applications.
Claims16
A rabbit monoclonal antibody,
- wherein said monoclonal antibody neutralizes TNFα activity.
A humanized rabbit monoclonal antibody that neutralizes TNFα activity.
Dependencies are inferred from the claim text.