Absorbable alpha-cyanoacrylate compositions
AssigneeEthicon, Inc.
InventorHongbo Liu
Life of this patent
Estimating the term…
Abstract
A monomer composition comprising at least one polymerizable alkyl ester α-cyanoacrylate monomer. Specifically, the α-cyanoacrylate monomer is an alkyl ester α-cyanoacrylate monomer of the general formula having a spacer R1: wherein n is from 2 to 12; R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; R2 is an alkyl group (e.g. linear or branched, or cyclic) having from 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 and 13 carbon atoms; and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.
Claims14
A monomer composition comprising at least one alkyl ester α-cyanoacrylate monomer of the formula:
- having a spacer
- wherein n is from 2 to 12;
- R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group having from about 1 to 13 carbon atoms;
- R2 is an alkyl group having from about 1 to 13 carbon atoms;
- and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.
A method of treating living tissue, comprising:
- applying to living tissue a monomer composition comprising at least one alkyl ester α-cyanoacrylate monomer of the formula:
- having a spacer R1,
- wherein n is from 2 to 12;
- R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group having from about 1 to 13 carbon atoms;
- R2 is an alkyl group having from about 1 to 13 carbon atoms;
- and the combined number of carbon atoms (N) in the spacer R1 is at least n+1.
A kit comprising a sealable package comprising:
- a first container that contains a monomer composition comprising at least one alkyl ester α-cyanoacrylate monomer of the formula:
- having a spacer R1,
- wherein n is from 2 to 12;
- R3 and R4 are each an alkyl group or a hydrogen, and at least one of R3 or R4 is an alkyl group having from about 1 to 13 carbon atoms;
- R2 is an alkyl group having from about 1 to 13 carbon atoms;
- and the combined number of carbon atoms (N) in the spacer R1 is at least n+1;
- and
- a second container that contains a polymerization initiator or accelerator.
Dependencies are inferred from the claim text.