Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin
AssigneeCiba Specialty Chemicals Holding Inc.
InventorsWerner Baschong, Marcel Schnyder
Life of this patent
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Abstract
The use of hydroxydiphenyl ether compounds of formula (I), wherein R1, R2 and R3 are each independently of the others hydrogen; hydroxy; C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; C1-C20alkoxy; C1-C6alkylcarbonyl; phenyl; or phenyl-C1-C3alkyl; R4 is hydrogen, C1-C20alkyl; hydroxy-substituted C1-C20alkyl; C5-C7cycloalkyl; hydroxy; formyl; acetonyl; allyl; carboxy; carboxy-C1-C3alkyl; carboxyallyl; C2-C20alkenyl; C1-C6alkylcarbonyl; C1-C3alkylcarbonyl-C1-C3alkyl; phenyl; or phenyl-C1-C3alkyl; and R5 is hydrogen; C1-C20alkoxy; or C1-C6alkylcarbonyl; as melanogenesis inhibitors and for lightening the skin.
Claims29
A method of inhibiting melanogenesis and for lightening skin, which comprises contacting said skin with a composition comprising
- (a) a halogenated hydroxydiphenyl ether compound of formula
- wherein
- Y is chlorine or bromine,
- Z is SO2H, NO2;
- or C1-C4alkyl;
- m is 0 or 1;
- n is 1 or 2;
- r is from 0 to 3;
- o is from 1 to 3;
- and
- p is 0, 1 or 2.
(canceled)
A cosmetic formulation, containing
- from 0.05 to 2% of component (a), selected from the compound of formula
- from 0.01 to 2% of component (b), selected from the compound of formula
- from 0.05 to 2 of % component (d), selected from the compound of formula
Dependencies are inferred from the claim text.