Buccal, polar and non-polar spray containing diazepam

An oral spray composition for transmucosal administration of diazepam or a pharmaceutically acceptable salt thereof comprising:

• diazepam or a pharmaceutically acceptable salt thereof in an amount of between 0.1 and 25 percent by weight of the total composition;
• a polar solvent in an amount between 10 and 97 percent by weight of the total composition;
• and a propellant in an amount between 2 and 10 percent by weight of the total composition, wherein said propellant is a C3 to C8 hydrocarbon of linear or branched configuration.

22-28. (canceled)

An oral spray composition for transmucosal administration of diazepam or a pharmaceutically acceptable salt thereof comprising:

• diazepam or a pharmaceutically acceptable salt thereof in an amount between 0.05 and 50 percent by weight of the total composition;
• and a non-polar solvent in an amount between 19 and 85 percent by weight of the total composition;
• and a propellant in an amount between 5 and 80 percent by weight of the total composition, wherein said propellant is a C3 to C8 hydrocarbon of linear or brancehed configuration.

An oral spray composition for transmucosal administration of diazepam or a pharmaceutically acceptable salt thereof comprising:

• diazepam or a pharmaceutically acceptable salt thereof in an amount between 0.2 and 10 percent by weight of the total composition;
• and a polar solvent comprising propylene glycol and ethanol in an amount between 50 and 99 percent by weight of the total composition.

41-48. (canceled)

An oral spray composition for transmucosal administration of diazepam or a pharmaceutically acceptable salt thereof comprising:

• diazepam or a pharmaceutically acceptable salt thereof in an amount between 0.05 and 50 percent by weight of the total composition;
• a mixture of a polar and a non-polar solvent in an amount between 10 and 97 percent by weight of the total composition, wherein the ratio of the polar solvent to the non-polar solvent ranges from 1:99 to 99:1;
• and a propellant in an amount between 5 and 80 percent by weight of the total composition, wherein said propellant is a C3 to C8 hydrocarbon of linear or branched configuration.

57-63. (canceled)

71-77. (canceled)

85-91. (canceled)