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US 2006/0216237 A1Published application
Inhibition of angiogenesis and tumor development by IGFBP-4
OwnerPeter Brooks, Abebe Akalu +2inventors
InventorsPeter Brooks, Abebe Akalu, Alexandra Cretu, Desiree Policarpio
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Abstract
The invention provides compositions comprising IGFBP-4 and methods for inhibiting angiogenesis and tumor development processes, and for treating angiogenesis-dependent conditions, using an insulin growth factor binding protein, IGFBP-4.
Claims6
A therapeutic composition comprising IGFBP-4 and a pharmaceutically acceptable excipient.
A method for inhibiting angiogenesis in a patient, treating a tumor in a patient, inhibiting metastases in a patient, or treating an angiogenesis-dependent condition in a patient, comprising:
- administering a therapeutically effective amount of IGFBP-4 to the patient.
Dependencies are inferred from the claim text.