Elution test method and apparatus

Abstract

An elution test method measures the elution process of a specific component in a process where a preparation containing at least the specific component subject to a change with time in chemical properties after elution and an impurity component not subject to a change with time in chemical properties after elution is eluted into a test liquid. The method obtains a ratio of absorbance k of the impurity component and a ratio of absorbance k′ of the specific component at two isosbestic point wavelengths λ1, λ2 in a spectrum including the specific component and its decomposed matter, and calculates at least one of the absorbances A1(t), A2(t) of said specific component by using k×C2(t)−C1(t)=k×A2(t)−A1(t) and A1(t)/A2(t)=k′ from the absorbance C1(t), C2(t) at said two isosbestic point wavelengths λ1, λ2 measured at the plural time points t in the elution process of said preparation, and converts the result to an elution concentration.

Dependencies are inferred from the claim text.