Mobile phase supplying apparatus, liquid chromatograph using the same, and mobile phase supplying method
AssigneeShimadzu Corporation
InventorTakaei Kitagawa
Life of this patent
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Abstract
In liquid-feeding sections for feeding two types of mobile phases A, B, respectively, actual flow rate measuring sections capable of detecting back-flows are provided in downstream of liquid-feeding pumps, respectively. Control devices control driving of the liquid feeding pumps, respectively, so that measured flow rates by the actual flow rate measuring sections correspond to set flow rates on the liquid-feeding flow paths, respectively. In a case where the set flow rate is zero, when either of the actual flow rate measuring sections detects the back-flow, the corresponding liquid-feeding pump is driven so as to prevent the back-flow.
Claims6
A mobile phase supplying apparatus of a high-pressure gradient system for supplying mobile phases while controlling a composition of the mobile phases, the mobile phase supplying apparatus comprising:
- a plurality of liquid-feeding pumps for feeding the mobile phases, respectively;
- a plurality of liquid-feeding flow paths having the liquid-feeding pumps, respectively;
- a mixer for mixing the mobile phases by merging the liquid-feeding flow paths;
- at least one control device for controlling driving of each of the liquid-feeding pumps based on flow rates being set for the respective liquid-feeding flow paths;
- and
- a plurality of actual flow rate measuring sections for measuring actual flow rates in the liquid-feeding flow paths respectively, each of the actual flow rate measuring sections being provided in downstream of the liquid-feeding pump in each of the liquid-feeding flow paths,
- wherein when the control device determines that a back-flow exists in the liquid-feeding flow path of which set flow rate is zero based on the measured flow rate, the control device controls the driving of the liquid-feeding pump in said liquid-feeding flow path so as to cancel the back-flow.
A mobile phase supplying method of a high-pressure gradient system for supplying mobile phases while controlling a composition of the mobile phases, the mobile phase supplying method comprising:
- measuring actual flow rates in a plurality of liquid-feeding flow paths respectively;
- controlling driving of each of a plurality of liquid-feeding pumps in each of the liquid-feeding flow paths based on flow rates being set for the respective liquid-feeding flow paths;
- and
- feeding the mobile phases through the liquid-feeding pumps into the liquid-feeding flow paths respectively,
- wherein when it is determined that a back-flow exists in the liquid-feeding flow path of which set flow rate is zero based on the measured actual flow rate, the driving of the liquid-feeding pump in said liquid-feeding flow path is controlled so as to cancel the back-flow.
Dependencies are inferred from the claim text.