Method for screening crystallization conditions using multifunctional substrates
AssigneeIllinois Institute of Technology
InventorsAllan Myerson, Alfred Lee
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Abstract
A method for producing crystals and for screening crystallization conditions of chemical materials on distinct metallic islands with specific functional groups by using multi-functional substrates comprising a plurality of self-assembled monolayers having at least two different functionalities, for preparing and screening conditions necessary to promote specific polymorphs of a crystal, and a means for testing and screening the more precise conditions suitable for achieving desired sizes or forms of a crystal.
Claims29
A method for the screening of crystallization conditions comprising the steps of:
- a) forming a plurality of metallic islands on a substrate;
- b) applying a first self-assembled monolayers comprising a first functional group to at least one of the metallic islands to form a first type of functionalized metallic island, and applying a second self-assembled monolayers comprising a second functional group different from the first functional group to at least another of the metallic islands to form a second type of functionalized metallic island;
- c) nucleating and growing crystals of a selected substance on the functionalized metallic islands;
- and
- d) after the crystals have formed on the functionalized metallic islands, analyzing the crystals.
A method for the screening of crystallization conditions comprising the steps of:
- a) forming a plurality of metallic islands on a substrate, wherein there are at least two different sizes of metallic islands on the substrate;
- b) applying a first self-assembled monolayers comprising a first functional group to at least one of the metallic islands to form a first type of functionalized metallic island, and applying a second self-assembled monolayers comprising a second functional group different from the first functional group to at least another of the metallic islands to form a second type of functionalized metallic island;
- c) nucleating and growing crystals of at least one selected substance on the functionalized metallic islands;
- and
- d) after the crystals have formed on the functionalized metallic islands, analyzing the crystals.
A method for the screening of crystallization conditions comprising the steps of:
- a) forming a plurality of metallic islands on a substrate;
- b) applying at least two different self-assembled monolayers comprising different functional groups to the metallic islands to form functionalized metallic islands;
- c) nucleating and growing crystals of a selected substance on functionalized metallic islands;
- and
- d) after the crystals have formed on the functionalized metallic islands, analyzing the crystals.
Dependencies are inferred from the claim text.