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US 2006/0193905 A1Published application
Direct cellular energy delivery system
AssigneeUniversity of Louisville Research Foundation, Inc.
InventorsWilliam Ehringer, Sufan Chien
Life of this patent
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Abstract
A lipid vesicle comprising a phospholipid which is a stable vesicle former and at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein is provided. The vesicle can further comprise a biomolecule, such as for example ATP. Methods of using the vesicle for delivery of biomolecules are also provided.
Claims48
A vesicle, comprising:
- (a) a phospholipid which is a stable vesicle former;
- and
- (b) at least one unstable vesicle forming member, wherein the unstable vesicle forming member is selected from the group consisting of a polar lipid which is not a stable vesicle former, a PEG, a raft former and a fusion protein.
A vesicle, comprising:
- a biomolecule;
- soy phosphatidylcholine;
- and
- DOTAP.
1 more element
A vesicle, comprising:
- a biomolecule;
- DOPC;
- and
- DOTAP.
1 more element
Dependencies are inferred from the claim text.