Least-square deconvolution (LSD): a method to resolve DNA mixtures
AssigneeUniversity of Tennessee Research Foundation
InventorsTse-Wei Wang, Ning Xue, John Birdwell, Mark Rader, John Flaherty
Life of this patent
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AssigneeUniversity of Tennessee Research Foundation
InventorsTse-Wei Wang, Ning Xue, John Birdwell, Mark Rader, John Flaherty
Estimating the term…
Least Square Deconvolution (LSD) uses quantitative allele peak area derived from a sample containing the DNA of more than one contributor to resolve the best-fit genotype profile of each contributor. The resolution is based on finding the least square fit of the mass ratio coefficients at each locus to come closest to the quantitative allele peak data. Consistent top-ranked mass ratio combinations from each locus can be pooled to form at least one composite DNA profile at a subset of the available loci. The top-ranked DNA profiles can be used to check against the profile of a suspect or be used to search for a matching profile in a DNA database.
A method of remotely accessing a software application for resolving a mixture of DNA comprising the steps of:
A method of remotely accessing a server for resolving a mixture of DNA containing DNA from more than one source, the method comprising the steps of:
A method of remotely accessing a software application for resolving a mixture of DNA of at least two contributors comprising the steps of:
Dependencies are inferred from the claim text.