Loading patent…
AssigneeBeth Israel Deaconess Medical Center, Inc.
InventorsAry Goldberger, Chung-Kang Peng, Madalena Costa
Estimating the term…
In a subject undergoing therapeutic intervention, efficacy of the therapeutic intervention is assessed based on a series of physiologic data associated with the subject. The series of physiologic data is analyzed to produce a measure of complexity. The complexity measure is then compared to a control. The efficacy of the therapeutic intervention is assessed based on the comparison of the complexity measure to the control. The control may be, for example, a complexity measure taken prior to initiation of the therapeutic intervention, a complexity measure taken from a different subject, or a predetermined threshold value. The measure of complexity is generated using, for example, a multiscale entropy measurement (MSE), a time asymmetry measurement, and/or an information-based similarity measurement. An increase in complexity indicates a positive effect of the therapeutic intervention, while a decrease in complexity indicates a negative effect of the therapeutic intervention.
A method of assessing efficacy of therapeutic intervention in a subject based on a series of physiologic data associated with the subject, comprising:
A computer program product comprising a computer useable medium having computer readable program code fuinctions embedded in the medium for causing a computer to assess efficacy of therapeutic intervention in a subject based on a series of physiologic data associated with the subject, comprising:
A computer-based system to assess efficacy of therapeutic intervention in a subject based on a series of physiologic data associated with the subject, comprising:
Dependencies are inferred from the claim text.