Apnea detection system
AssigneePrecision Pulsus, Inc.
InventorDonald Arnold
Life of this patent
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Abstract
A method and apparatus are described for utilizing a source of vascular pulse waveform data from a patient for the purpose of measuring pulsus paradoxus. The arterial pulse waveform data source described is a pulse oximeter plethysmograph but can be any similar waveform data source, including an intra-arterial transducer, external blood pressure transducer, or plethysmograph. Through incorporation of measurements of values, such as an area under a pulse waveform curve, that are time-domain functions of a change in amplitude of the pulse waveform over a duration of the waveform, embodiments of the present invention represent a significant improvement upon previously described methods of measuring pulsus paradoxus.
Claims32
A method, for detecting apnea in a mammal, comprising:
- obtaining data indicative of pulsatile cardiovascular behavior from the mammal, the data comprising at least a first and a second pulse waveform;
- determining a first value of a function of a change in amplitude of the first pulse waveform, with respect to time, over at least a partial duration of the first pulse waveform;
- determining a second value of a function of a change in amplitude of the second pulse waveform, with respect to time, over at least a partial duration of the second pulse waveform;
- determining at least one of a probability of apnea, a presence of apnea, and an absence of apnea based on a comparison of the first value and the second value.
A method for measuring pulsus paradoxus in a mammal, the method comprising:
- obtaining data indicative of pulsatile cardiovascular behavior from the mammal, the data comprising a first plethysmographic or pressure amplitude obtained at a first time interval after an onset of a first pulse, and a second plethysmographic or pressure amplitude obtained at a second time interval after the onset of the first pulse;
- determining a first value of a function of a difference between the first and second plethysmographic or pressure amplitudes;
- obtaining a third plethysmographic or pressure amplitude obtained at the first time interval after an onset of a second pulse, and a fourth plethysmographic or pressure amplitude obtained at the second time interval after the onset of the second pulse;
- determining a second value of a function of a difference between the third and fourth plethysmographic or pressure amplitudes;
- comparing the first value and the second value to determine a value of pulsus paradoxus;
- and
- comparing the pulsus paradoxus value with at least one of a predetermined value and range so as to determine at least one of a probability of apnea, a presence of apnea, and an absence of apnea.
A system for measuring pulsus paradoxus in a mammal, the system comprising:
- means for obtaining data indicative of pulsatile cardiovascular behavior from the mammal, the data comprising at least components of a first and a second pulse waveform;
- means for comparing a value of a time-domain function of a change in amplitude of the first pulse waveform over at least a partial duration of the first pulse waveform, with a value of a time-domain function of a change in amplitude of the second pulse waveform over at least a partial duration of the second pulse waveform, so as to determine at least one of a probability of apnea, a presence of apnea, and an absence of apnea.
A system for measuring pulsus paradoxus in a mammal, the system comprising:
- a detector module that obtains data indicative of pulsatile cardiovascular behavior from the mammal, the data comprising at least components of a first and a second pulse waveform;
- a comparing module that compares a first AUC from at least one component of the first pulse waveform, and a second AUC from at least one component of the second pulse waveform, so as to determine at least one of a probability of apnea, a presence of apnea, and an absence of apnea.
A system for measuring pulsus paradoxus in a mammal, the system comprising:
- a detector module that obtains data indicative of pulsatile cardiovascular behavior from the mammal, the data comprising at least components of a first and a second pulse waveform;
- a comparing module that compares a value of a function of a change in amplitude of the first pulse waveform over at least a partial duration of the first pulse waveform, with a value of a function of a change in amplitude of the second pulse waveform over at least a partial duration of the second pulse waveform, so as to determine at least one of a probability of apnea, a presence of apnea, and an absence of apnea.
Dependencies are inferred from the claim text.