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US 2006/0189785 A1Published application
Micellar drug delivery systems for hydrophobic drugs
AssigneeThe University of British Columbia
InventorsJohn Jackson, Jason Zastre, Helen Burt
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Abstract
This invention provides compositions comprising a hydrophobic drug, a biocompatible micelle forming polymer, and a biocompatible low molecular weight, water-soluble polymer. Also provided are devices for injection of such compositions and for the use of such compositions to form hydrophobic drug containing micelles within the body of a patient.
Claims40
A micelle forming composition comprising:
- (a) one or more hydrophobic drugs;
- (b) one or more biocompatible, micelle forming polymers;
- and,
- (c) one or more biocompatible, low molecular weight, water soluble polymers,
- wherein the one or more water soluble polymers are present in an amount sufficient that the composition is injectable.
2 more elements
A micelle forming composition comprising:
- (a) one or more hydrophobic drugs;
- (b) one or more biocompatible, micelle forming polymers;
- and,
- (c) one or more biocompatible, low molecular weight, water soluble polymers,
- wherein the micelle forming polymer is a block copolymer comprising a hydrophobic and a hydrophilic portion, the hydrophobic portion comprising a polymer block selected from the group consisting of:
- a polyester and a polyanhydride;
- and, the hydrophilic portion is a polyethylene oxide having a molecular weight of about 750 or more.
4 more elements
Dependencies are inferred from the claim text.