Use of urocanic acid being able to acidify the cell cytoplasm and for preventing or halting cellular proliferation in a person
OwnerLasse Leino, Jarmo Laihiainventors
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Abstract
The use of urocanic acid or another pharmaceutically acceptable agent being able to acidify the cell cytoplasm, for the manufacture of a pharmaceutical composition useful for causing inhibition or halting of transformed or non-transformed cell proliferation in a person or an animal, where an effective amount of the agent is administered in an essentially non-dissociated form to the person or animal. The use of the agent as an enhancer for other therapeutically active agents, and a pharmaceutical composition, are also disclosed.
Claims19
1-15. (canceled)
A method for preventing or halting cellular proliferation in a person or an animal, comprising administering an effective amount of said cis-urocanic acid in an essentially non-dissociated form to the person or animal in the form of a pharmaceutical composition.
A method for enhancing the effect of a therapeutically active agent, comprising administering said therapeutically active agent to a human or animal in need of said treatment in combination with cis-urocanic acid.
Pharmaceutical composition comprising a therapeutically active agent, an enhancer for said agent and a pharmaceutically acceptable agent being able to acidify the cell cytoplasm, in combination with a pharmaceutically acceptable carrier, which carrier essentially prevents the enhancer from dissociating at extracellular pH values.
Dependencies are inferred from the claim text.