Anilinoquinazaolines as protein tyrosine kianse inhibitors

A compound of formula (I)

• or a salt thereof;
• wherein
• X is CR1 and Y is N;
• R1 represents a group R5SO2CH2CH2Z-(CH2)p—Ar—, wherein Ar is furan, which may optionally be substituted by one or two halo, C1-4 alkyl or C1-4 alkoxy groups;
• Z represents O, S, NH or NR6;
• p is 1, 2, 3 or 4;
• R5 is C1-6 alkyl optionally substituted by one or more R8 groups;
• or
• R5 is C1-6 alkyl substituted by a 5 to 10-membered heterocyclic group or a 3 to 10-membered carbocyclic group, each of which may be optionally substituted by one or more R8 groups;
• or
• R5is selected from the group consisting of a 5 to 10-membered heterocyclic group or a 3 to 10-membered carbocyclic group, each of which may be optionally substituted by one or more R8 groups;
• each R8 is independently selected from halo, hydroxy, C1-4 alkoxy, nitrile, NH2 or NR6R7;
• R6 is C1-4 alkyl, C1-4 alkoxy-C14alkyl, hydroxyC14alkyl, cyanomethyl, benzyl, CF3C(O) or CH3C(O);
• R7 is hydrogen or R6;
• R3 is selected from pyridylmethoxy, benzyloxy, halo-, dihalo- and trihalobenzyloxy;
• R4 is selected from hydrogen, halogen, C1-4 alkyl, C2-4 alkynyl or cyano.