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US 2006/0189607 A1Published application
Long-acting betamimetics for the treatment of respiratory complaints
AssigneeBoehringer Ingelheim International GmbH
InventorsIngo Konetzki, Christoph Hoenke, Thierry Bouyssou, Andreas Schnapp
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Abstract
The present invention relates to compounds of formula 1, wherein n, A, R1, R2 and R3 may have the meanings specified in the description and claims, processes for preparing them and their use as pharmaceutical compositions, particularly as pharmaceutical compositions for the treatment of respiratory complaints.
Claims8
1) A compound of formula 1,
- wherein
- n denotes 1, 2, 3 or 4;
- A denotes a double-bonded group selected from among —O, —CR4R5, —NR6, —S, —CR4R5—O, —CR4R5—NR6, —CH═CH or —CH2—CH2—;
- R1 denotes —C1-6-alkyl;
- R2 and R3, which may be identical or different, denote H, C1-6-alkyl, C2-6-alkenyl, C2-6-alkynyl, C3-6-cycloalkyl, C1-6-haloalkyl, —O—C1-6-haloalkyl, halogen, OH, CN, NO2, O—C1-6-alkyl, —C2-6alkyl-OH, NH2, NH—C1-6-alkyl, N(C1-6-alkyl)2, NHCO—C1-6-alkyl, NHSO2—C1-6-alkyl, S—C1-6-alkyl, SO—C1-6-alkyl, SO2—C1-6-alkyl, SO2NH2, SO2NH—C1-6-alkyl, SO2N(C1-6-alkyl)2, CONH2, CONH—C1-6-alkyl, CON(C1-6-alkyl)2, —CO—C1-6-alkyl, COOH or COO—C1-4-alkyl, or
- R2 and R3 together denote a double-bonded group selected from —O—CR4R5—O, —O—CR4R5—NR6 or —CH═CH—CH═CH—;
- R4 denotes H or C1-6-alkyl;
- R5 denotes H or C1-6-alkyl;
- R6 denotes H or C1-6-alkyl,
- optionally in the form of an individual enantiomer thereof, a mixture of the individual enantiomers or a racemate, optionally in the form of a pharmacologically acceptable acid addition salt thereof, as well as optionally in the form of a solvate and/or a hydrate thereof.
7 more elements
Dependencies are inferred from the claim text.