Use for budesonide and formoterol
AssigneeAstra Aktiebolag, a Swedish corporation
InventorsCarl-Axel Bauer, Jan Trofast
Life of this patent
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Abstract
The invention provides the use of formoterol and budesonide in the treatment of chronic obstructive pulmonary disease.
Claims10
Use of a composition comprising, in admixture or separately:
- (a) a first active ingredient which is formoterol, a pharmaceutically acceptable salt or solvate thereof, or a solvate of such a salt;
- (b) a second active ingredient which is budesonide;
- and a molar ratio of the first active ingredient to the second active ingredient of from 1:2500 to 12:1,
- in the manufacture of a medicament for use in the treatment of chronic obstructive pulmonary disease:
Use of a kit containing:
- (i) a vessel containing a first active ingredient which is formoterol, a pharmaceutically acceptable salt or solvate thereof, or a solvate of such a salt;
- (ii) a vessel containing a second active ingredient which is budesonide;
- (iii) a molar ratio of the first active ingredient to the second active ingredient of from 1:2500 to 12:1;
- and
- (iv) instructions for the simultaneous, sequential or separate administration of the first and second active ingredients to a patient in need thereof;
- in the manufacture of a medicament for use in the treatment of chronic obstructive pulmonary disease.
Use according to any one of the preceding claims, wherein the first active ingredient is formoterol fumarate dihydrate.
Use according to any one of the preceding claims, wherein the molar ratio of the first active ingredient to the second active ingredient is from 1:555 to 2:1, preferably from 1:70 to 1:4.
A method for the treatment of a patient suffering from chronic obstructive pulmonary disease which method comprises administering to the patient via inhalation, simultaneously, sequentially or separately, a therapeutically effective amount of (i) a dose of a first active ingredient which is formoterol, a pharmaceutically acceptable salt or solvate thereof, or a solvate of such a salt;
- and (ii) a second active ingredient which is budesonide, and wherein the molar ratio of the first active ingredient to the second active ingredient is from 1:2500 to 12:1.
Dependencies are inferred from the claim text.