Modification of feeding behaviour
OwnerStephen Bloom, Mohammad Ghatei +2inventors
InventorsStephen Bloom, Mohammad Ghatei, Caroline Small, Catherine Dakin
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Abstract
The present invention relates to compositions and methods for use in the prevention or treatment of excess weight in a mammal. The compositions comprise oxyntomodulin which is shown to reduce food intake and/or increase energy expenditure.
Claims25
1-37. (canceled)
A pharmaceutical composition comprising oxyntomodulin and one or more additional agents which influence weight and/or food intake.
A method for decreasing calorie intake in a subject, for decreasing appetite in a subject, for decreasing food intake in a subject, for increasing energy expenditure in a subject, for weight control or treatment in a subject, for reduction or prevention of obesity in a subject;
- for preventing and reducing weight gain in a subject;
- for inducing and promoting weight loss in a subject;
- a method for reducing obesity as measured by the Body Mass Index;
- a method for controlling of any one or more of appetite, satiety and hunger in a subject;
- a method for maintaining desired body weight, a desired Body Mass Index, and/or a desired appearance and good health in a subject;
- a method for improving lipid profile in a subject;
- a method for alleviating a condition or disorder in a subject, which condition or disorder can be alleviated by reducing nutrient availability and/or by increasing energy expenditure;
- or a method for reducing levels of circulating ghrelin in a subject, which comprises administering oxyntomodulin and one or more additional agents, which influence weight and/or food intake to the subject
Dependencies are inferred from the claim text.