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AssigneeCaliper Life Sciences, Inc.
InventorsMichael Spaid, Andrea Chow, Yevgeny Yurkovetsky, Seth Stern, Allen Boronkay, Morten Jensen, Carlton Brooks, Ken Swartz
Estimating the term…
A microfluidic system and method for employing it to control fluid temperatures of fluids residing within microchannels of a microfluidic device. The microfluidic device is provided with a top layer and a bottom layer and microchannels configured therebetween. Temperature of the fluid within the microchannels is controlled in various ways including the use of electrical resistive heating elements and by providing zones located in contact with the top and bottom layers of the microfluidic device for circulating heat transfer of fluid therein.
A method of controlling temperature of fluids residing within microchannels of a microfluidic device, said microfluidic device having a top layer and a bottom layer and microchannels configured therebetween, said method comprising applying heat transfer fluid to said top layer or said bottom layer or to both said top and bottom layers of said microfluidic device.
13-20. (canceled)
A method of controlling temperature of fluids residing within microchannels of a microfluidic device, said microfluidic device having a top layer and a bottom layer and a plurality of microchannels configured therebetween, said method comprising creating non-uniform spacing between said plurality of microchannels to enhance uniformity of temperature of said fluids residing within said plurality of microchannels.
A method of controlling temperature of fluids residing within microchannels of a microfluidic device, said microfluidic device having a top layer and a bottom layer and a plurality of microchannels configured therebetween and electrically resistive heating elements associated with said plurality of microchannels for transferring energy to said fluids residing therein, said method comprising creating non-uniform spacing between said electrically resistive heating elements to enhance uniformity of temperature of said fluids residing in said plurality of microchannels.
A method of controlling temperatures of fluids residing within microchannels of a microfluidic device, said microfluidic device having a top layer, bottom layer, longitudinal axis and a plurality of microchannels, each having a longitudinal axis configured therebetween and parallel to said longitudinal axis of said microfluidic device wherein said microchannels are created with non-uniform channel dimensions along said longitudinal axis.
27-35. (canceled)
Dependencies are inferred from the claim text.