Artificial enzyme and method for producing the same

An artificial enzyme which exhibits enzyme activity to a target reaction and is produced by a method for producing an artificial enzyme, wherein the method for producing an artificial enzyme comprises the steps of:

• selecting an artificial enzyme precursor which comprises an oligonucleotide sequence containing modified nucleosides prepared by introducing a substituent into each nucleoside and at least one of the modified nucleoside capable of reacting with a raw substance of a target reaction which the artificial enzyme catalyzes;
• and
• producing the artificial enzyme which is capable of catalyzing the target reaction and comprises the oligonucleotide sequence in which the modified nucleoside capable of reacting with the raw substance of the artificial enzyme precursor is substituted with a non-reactive modified nucleoside which is non-reactive with the raw substance of the target reaction.