Implantation serine proteinases
OwnerDerrick Rancourt, Susan Rancourt +1inventors
InventorsDerrick Rancourt, Susan Rancourt, Colleen O'Sullivan
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Abstract
This invention provides three novel serine proteinases that are important for female fertility, particularly in the process of hatching and implantation. These proteinases, as well as the nucleic acids, fragments, analogs, and/or inhibitors thereof, can be used to modulate hatching, implantation and female fertility in general.
Claims16
An isolated DNA encoding a protein comprising the sequence as set forth in SEQ ID NO:
- 27.
A method for producing a recombinant ISP protein, comprising constructing an expression vector comprising a DNA that encodes a protein having SEQ ID NO:
- 27, introducing the expression vector into a suitable cell and selecting transformants, culturing the transformants under conditions that result in production of the ISP protein, and recovering the ISP protein.
An isolated DNA that encodes a protein that is at least 90% identical to the sequence as set forth in SEQ ID NO:
- 27, wherein said DNA encodes a protein with ISP biological activity.
Dependencies are inferred from the claim text.