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US 2006/0188480 A1Published application
Viral vectors
AssigneeBiovex Limited
InventorsRobert Coffin, Guy Simpson
Life of this patent
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Abstract
The present invention provides a herpes virus which lacks a functional ICP34.5 encoding gene and which comprises two or more of—(i) a gene encoding a prodrug converting enzyme; (ii) a gene encoding a protein capable of causing cell to cell fusion; and (iii) a gene encoding an immunomodulatory protein.
Claims21
A herpes virus which lacks a functional ICP34.5 encoding gene and which comprises two or more of:
- (i) a heterologous gene encoding a prodrug converting enzyme;
- (ii) a heterologous gene encoding a protein capable of causing cell to cell fusion;
- and
- (iii) a heterologous gene encoding an immunomodulatory protein.
1 more element
(canceled)
(canceled)
(canceled)
Dependencies are inferred from the claim text.