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OwnerXiaochuan Zhou, Tiecheng Zhou +1inventors
InventorsXiaochuan Zhou, Tiecheng Zhou, David Sun
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Fluidic methods and devices for conducting parallel chemical reactions are disclosed. The methods are based on the use of in situ photogenerated reagents such as photogenerated acids, photogenerated bases, or any other suitable chemical compounds that produce active reagents upon light radiation. The present invention describes devices and methods for performing a large number of parallel chemical reactions without the use of a large number of valves, pumps, and other complicated fluidic components. The present invention provides microfluidic devices that contain a plurality of microscopic vessels for carrying out discrete chemical reactions. Other applications may include the preparation of microarrays of DNA and RNA oligonucleotides, peptides, oligosacchrides, phospholipids and other biopolymers on a substrate surface for assessing gene sequence information, screening for biological and chemical activities, identifying intermolecular complex formations, and determining structural features of molecular complexes.
A microfluidic reactor comprising a plurality of reaction cells
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A microfluidic reactor according to claim 50, wherein the reactor further comprises immobilized molecules in a double-layer configuration in the reaction cell.
A microfluidic reactor according to claim 50, wherein the reactor further comprises a three-dimensional attachment of immobilized molecules in the reaction cell.
A microfluidic reactor according to claim 50, further comprising porous films in the reaction cell.
A microfluidic reactor according to claim 50, wherein the reaction cells are in capillary form.
A microfluidic reactor comprising at least one microfluidic template and at least one window plate attached to the template, the microfluidic template and the window plate defining a plurality of reaction cells and a plurality of tapered fluid channels, wherein each fluid channel is in fluid communication with a plurality of said reaction cells.
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Dependencies are inferred from the claim text.