Rotary blending apparatus and system

A rotary blending apparatus for mixing a pharmaceutical composition, comprising:

• a hub having an outer diameter in the range of 139.0 to 141.0 mm;
• and
• a plurality of substantially angularly spaced impeller blades, each of said impeller blades having a first and second baffle,
• said first baffle having first and second ends, a first length in the range of 245.0 to 247.0 mm and a first width in the range of 70.0 to 75.0 mm,
• said first end of said first baffle being rigidly connected to said hub, said first baffle forming a first impeller angle with respect to the vertical axis of said hub in the range of approximately 110°-130°, said second end of said first baffle having a substantially linear edge forming a second impeller angle with respect to the longitudinal axis of said hub in the range of 40°-50°,
• said second baffle having first and second ends, a second length in the range of 139.0 to 141.0 mm and a second width in the range of 96.0 to 98.0 mm,
• said first end of said second baffle being rigidly connected to said second end of said first baffle, said first and second baffles forming a third impeller angle in the range of approximately 85°-95°,
• said hub outer diameter, said first and second lengths, said first and second widths, and said first, second and third impeller angles defining a first blending apparatus size have a first tip radius, said first blending apparatus size providing a first flow pattern of said composition during rotation of said apparatus,
• said apparatus being scalable to at least a second blending apparatus size having a second tip radius, said second blending apparatus size providing a second flow pattern that is substantially similar to said first flow pattern.

A rotary blending system for mixing a composition, comprising:

• a mixing container having a mixing chamber;
• a rotatable drive shaft;
• and
• a rotary blending apparatus disposed in said mixing chamber, said rotary blending apparatus being connected to said drive shaft, said rotary blending apparatus including a hub and a plurality of substantially angularly spaced impeller blades, each of said impeller blades having a first and second baffle, said first baffle having first and second ends, said first end being rigidly connected to said hub, said first baffle forming a first impeller angle with respect to the vertical axis of said hub in the range of approximately 110°-130°, said second end of said first baffle having a substantially linear edge forming a second impeller angle with respect to the longitudinal axis of said hub in the range of 40°-50°, said second baffle having first and second ends, said first end of said second baffle being rigidly connected to said second end of said first baffle, said first and second baffles forming a third impeller angle in the range of approximately 85°-95°.