Novel mucin-like polypeptides
OwnerJadwiga Bienkowska, Gregg McAllisterinventors
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Abstract
The present invention discloses open reading frame (ORFs) in human genome encoding for novel mucin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of disease.
Claims27
An isolated polypeptide having mucin-like activity selected from the group consisting of:
- (a) the amino acid sequence as recited in SEQ ID NO:
- 2, SEQ ID NO:
- 3 or SEQ ID NO:
- 7;
- (b) the mature form of the polypeptide whose sequence is recited in (a);
- (c) an amino acid sequence at least 85% identical to the amino acid sequence recited in (a);
- (d) a fusion protein of a polypeptide of (a), (b) or (c);
- and
- (e) a salt of (a), (b), (c) or (d).
2-5. (canceled)
(canceled)
(canceled)
(canceled)
15-16. (canceled)
19-20. (canceled)
25-28. (canceled)
30-37. (canceled)
Dependencies are inferred from the claim text.