Retrograde perfusion of tumor sites
OwnerReynaldo Calderoninventor
Life of this patent
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Abstract
A system and method permit monitoring and location of a route in vivo and a visible image of that route for retrograde perfusion of a tumor with a therapeutic agent. Once the route is located, the path for flow of therapeutic agent to the tumor is confirmed as being a closed loop. The therapeutic agent is then introduced into the closed loop through retrograde perfusion to treat the tumor. The number of types and amounts of treating agents may be adjusted and observed as the treatment is in progress.
Claims20
A method of retrograde venous perfusion of a tumor in a patient's body, comprising the steps of:
- positioning a withdrawal catheter within vasculature of a target vessel in the patient's body near the tumor;
- positioning an infusion catheter within the vasculature of the target vessel extending beyond the withdrawal catheter and near the tumor;
- positioning a venous pressure catheter within the vasculature of the target vessel intermediate the infusion catheter and the withdrawal catheter forming a closed loop flow path between the positioned infusion catheter and the positioned withdrawal catheter through the target vessel;
- monitoring venous pressure in the closed loop flow paths;
- and
- circulating a fluid through the closed loop flow path.
A treatment unit for retrograde perfusion of a tumor in a patient's body, comprising:
- an withdrawal catheter for positioning within vasculature of a target vessel in the patient's body near the tumor;
- an infusion catheter located within the withdrawal catheter for positioning within the vasculature of the target vessel vasculature of the patient's body near the tumor;
- and
- a venous pressure monitoring catheter for positioning within the vasculature of the target vessel intermediate the infusion catheter and the withdrawal catheter.
Dependencies are inferred from the claim text.