System for determining endothelial dependent vasoactivity
AssigneeRamot at Tel-Aviv University Ltd.
InventorsGiora Amitzur, Shmuel Einav, Eran Peleg, Elya Zimmerman
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Abstract
A method of determining endothelial dependent vasoactivity of a subject, the method is effected by recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel; extracting at least one parameter from the pressure-related signals; and using the at least one parameter to determine a change of at least one characteristic of the at least one blood vessel, the change being representative of endothelial functioning; thereby determining the endothelial dependent vasoactivity of the subject.
Claims55
A method of determining endothelial dependent vasoactivity of a subject, the method comprising:
- recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel;
- extracting at least one parameter from said pressure-related signals;
- and
- using said at least one parameter to determine a change of at least one characteristic of said at least one blood vessel, said change being representative of endothelial functioning;
- thereby determining the endothelial dependent vasoactivity of the subject.
A system for determining endothelial dependent vasoactivity of a subject, the system comprising:
- an arrangement of sensors for recording pressure-related signals of a plurality of locations adjacent to at least one blood vessel;
- a processing unit operable to receive, record and process said pressure-related signals;
- said processing unit being designed and programmed to extract at least one parameter from said pressure-related signals, and to use said at least one parameter to determine a change of at least one characteristic of said at least one blood vessel, said change being representative of endothelial functioning.
A method of determining endothelial dependent vasoactivity of a subject, the method comprising:
- (a) applying a first stimulus to at least one blood vessel;
- (b) measuring a pulse wave velocity of blood flowing in said at least one blood vessel;
- (c) determining an autonomic nervous system activity of the subject;
- (d) correlating said pulse wave velocity and said autonomic nervous system activity, so as to obtain a correlation function having an index;
- and
- (e) if said index has a predetermined value then:
- (i) applying a second stimulus on said at least one blood vessel;
- and
- (ii) repeating said steps (b)-(c);
- thereby determining the endothelial dependent vasoactivity of the subject.
Dependencies are inferred from the claim text.