Process for producing chain oligolactic acid ester
OwnerMikio Watanabe, Masahiro Murakamiinventors
Life of this patent
Estimating the term…
Abstract
An object of the present invention is to establish a method for directly synthesizing an oligolactic acid ester having a specific chain length as a single compound. According to the present invention, there is provided a method for producing a compound represented by formula (1): (in the formula (1), X represents a hydrogen atom or a protective group for a hydroxyl group, Y represents a hydrogen atom or a lower alkyl group, and p represents an integer of 2 to 19, satisfying m+n+1=p), which comprises reacting a compound represented by formula (2) defined in the specification with a compound represented by formula (3) defined in the specification.
Claims10
A method for producing a compound represented by formula (1):
- (in the formula (1), X represents a hydrogen atom or a protective group for a hydroxyl group, Y represents a hydrogen atom or a lower alkyl group, and p represents an integer of 2 to 19, satisfying m+n+1=p),
- which comprises reacting a compound represented by formula (2) with a compound represented by formula (3):
- (in the formula (2), X1 represents a protective group for a hydroxyl group, and m represents an integer of 0-18;
- and in the formula (3), Y1 represents a lower alkyl group, and n represents an integer of 0-18).
A method for deprotecting selectively a protective group for a hydroxyl group in the formula (1):
- wherein X represents a protective group for a hydroxyl group, Y represents a lower alkyl group, and m represents an integer of 1 to 19,
- wherein the compound represented by the formula (1) is treated with hydrofluoric acid.
A method for deprotecting selectively a protective group for a carboxyl group in the formula (1):
- wherein X represents a protective group for a hydroxyl group, Y represents a lower alkyl group, and m represents an integer of 1 to 19,
- wherein the compound represented by the formula (1) is treated with trifluoroacetic acid/methylene chloride.
Dependencies are inferred from the claim text.