Capsaicinoid gel formulation and uses thereof
AssigneeAlgoRx Pharmaceuticals, Inc.
InventorsRonald Burch, Timothy Anderson, Jeff Lazar
Life of this patent
Estimating the term…
Abstract
The present invention provides capsaicinoid gel formulations and methods for relieving pre- and post-surgical pain at a site in a human or animal by administering at a surgical site in a human or animal in need thereof a dose of capsaicinoid gel in an amount effective to attenuate post-surgical pain at the surgical site, the dose of capsaicin ranging from 100 μg to 10,000 μg.
Claims63
A method for treating post-surgical pain at a site in a human or animal comprising:
- administering intra-operatively at a surgical site in a human or animal in need thereof a single dose of capsaicinoid gel in an amount effective to attenuate or relieve post-surgical pain at the surgical site without eliciting an effect outside the surgical site and to attenuate or relieve pain emanating from the surgical site, the dose ranging from about 100 μg to about 10,000 μg capsaicin or a therapeutically equivalent dose of a capsaicinoid other than capsaicin.
A topical gel formulation for attenuating or relieving post-surgical pain at a surgical site in a human or animal in need thereof, comprising a capsaicinoid selected from the group consisting of from 100 μg to 10,000 μg of capsaicin, a therapeutically equivalent amount of one or more other capsaicinoids, and combinations thereof, a pharmaceutically and physiologically acceptable base and a pharmaceutically and physiologically acceptable gelling agent.
Dependencies are inferred from the claim text.