US 2006/0148898 A1 · Curing and prophylactic agent applied during the use of alcohol and psychoactive substances

Abstract

The invention relates to medicine and is directed at developing means and methods for narcological practice and for preventive measures in order to reduce the risk of falling sick with such menacing modem diseases like dependence diseases, in particular alcoholism, narcomania and toximania. Said invention provides for using already known chemical compounds, i.e. vicinal dithioglycols for developing medical agents exhibiting properties for preventing contraction or development or reducing the speed of pathological processes forming a base for dependence diseases, in particular withdrawal syndromes. The inventive substances reduce or block pharmacological effects resulting from ethanol injection and/or narcotics, thereby directly influencing pathogenic mechanisms of the dependence diseases, in particular alcoholism. It is stated that said agents are particularly efficient when they are perorally administered. Said invention is accompanied by experimental material which proves the large perspective of the inventive agents and of a prophylactic method which provides for the use thereof before and after consuming alcohol-containing beverages or narcotics. The use of the invention makes it possible to reduce the degree of falling sick with alcoholism and narcomania and to reduce the toxic action of alcohols during the household use thereof.

Claims20

Dependent claims

A method for the prevention of beginnings and/or for the prevention of development and/or for reducing the rate of development of pathological processes caused by the use of alcohol-containing beverages and/or substances having an addictive potential, comprising (a) providing a preparation comprising at least one vicinal dithioglycol of general chemical formula (1):

R1CH(SH)CH(SH)R2 (1)
where R1 is selected from the groups:
(—H) or (—COOH), or (—SO3H);
R2 is selected from the groups:
(—H) or (—COOH), or (—OH), or (—CH2—COOH), or (—CH2—OH), or (—CH2—SO3H), or (—CH2—O—CH2—SO3H);
or salts of derivatives thereof, comprising salt forming groups (—OH) or (—COOH), or (—SO3H);
and (b) administering the preparation to a subject by peroral or nasal administration in an effective amount.

4 more elements

A method for the treatment or prevention of conditions or pathological processes in which the formation of tetrahydroisoquinolines (THIQs) can take place in the organism, which method provides for preparing a composition comprising as at least one vicinal dithioglycol of general formula (1) for blocking and/or preventing the development and/or for reducing the rate of development of pathological processes caused by using alcohol-containing beverages and/or substances having an addictive potential.

Dependencies are inferred from the claim text.

Curing and prophylactic agent applied during the use of alcohol and psychoactive substances

Life of this patent

Curing and prophylactic agent applied during the use of alcohol and psychoactive substances

Life of this patent

Abstract

Claims20