Back to results
US 2006/0148836 A1Published application
Pyridyl-substituted spiro-hydantoin compounds and use thereof
AssigneeBristol-Myers Squibb Company
InventorsT.G. Dhar, Michele Launay, Dominique Potin, Scott Watterson, Zili Xiao
Life of this patent
Estimating the term…
Abstract
A class of substituted spiro-hydantoin compounds (II) having the formula: its pharmaceutically acceptable salts, enantiomers, solvates, or prodrugs thereof, wherein R16 is a substituted pyridinyl group, as defined herein, is provided. Pharmaceutical compositions and methods of treating anti-inflammatory and/or immune diseases with the pyridyl-substituted spiro-hydantoin compounds are also objectives of this invention.
Claims11
A compound according to formula II:
- its enantiomers, pharmaceutically-acceptable salts, or solvates, thereof, wherein:
- each R17 is independently —OR18, —NR18R19, —C(═O)R18, —CO2R18, —C(═O)NR18R19, —NR18C(═O)R19, —NR18C(═O)OR19, —S(O)pR19, —NR18SO2R19, and/or —SO2NR18R19;
- R18 and R19 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, and/or substituted cycloalkyl;
- q is 1, 2, or 3;
- and
- p is 1 or 2.
3 more elements
Dependencies are inferred from the claim text.