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US 2006/0148821 A1Published application
N,N-disubstituted diazocycloalkanes
AssigneeRecordati S.A.
InventorsAmedeo Leonardi, Gianni Motta, Carlo Riva, Rodolfo Testa
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Abstract
N,N-Disubstituted diazocycloalkanes of the formula I (R1=halogen, R2=(C3-C8)-cycloalkyl, R3=(C1-C4)-alkoxy or (C1-C4)-haloalkoxy group, m is 1 or 2 and n is 1 or 2, have affinity for serotonergic receptors. These compounds and their enantiomers, diastereoisomers, N-oxides, polymorphs, solvates and pharmaceutically acceptable salts are useful in the treatment of patients with neuromuscular dysfunction of the lower urinary tract and diseases related to 5-HT1A receptor.
Claims23
A compound having the general formula I
- wherein:
- R1 represents a halogen atom,
- R2 represents a (C3-C8)-cycloalkyl group,
- R3 represents a (C1-C4)-alkoxy,
- m is 1 or 2, and
- n is 1,
- or an enantiomer, optical isomer, diastereomer, N-oxide, crystalline form, hydrate, solvate or pharmaceutically acceptable salt thereof.
4 more elements
6-9. (canceled)
15-16. (canceled)
(canceled)
26-27. (canceled)
Dependencies are inferred from the claim text.