Chroman derivatives and uses thereof

A compound of formula I:

• or a pharmaceutically acceptable salt thereof,
• wherein:
• m is from 0 to 3;
• p is from 1 to 3;
• q is 0, 1 or 2;
• Ar is optionally substituted aryl or optionally substituted heteroaryl;
• each R1 is independently halo, alkyl, haloalkyl, heteroalkyl, cyano, —S(O)t—Ra, —C(═O)—NRbRc, —SO2—NRbRc, —N(Rd)—C(═O)—Re, —C(═O)N(Rd)—, or —C(═O)—Re, where t is from 0 to 2, Ra, Rb, Rc, Rd and Re each independently is hydrogen or alkyl, and Rf is hydrogen, alkyl, alkoxy or hydroxy;
• R7 is
• X is —O— or —NR9—;
• n is 2 or 3;
• R3, R4, R5 and R6 each independently is hydrogen or alkyl;
• R7 and R8 each independently is hydrogen or alkyl, or R7 and R8 together with the nitrogen to which they are attached may form a four-to-six-membered ring that optionally includes an additional heteroatom selected from O, N and S, or one of R7 and R8 and one of R5 and R6 together with the atoms to which they are attached may form a four-to-six-membered ring that optionally includes an additional heteroatom selected from O, N and S;
• and
• R9 is hydrogen or alkyl, or when R7 is hydrogen or methyl, R9 together with R8 and the atoms to which they are attached may form a six-membered ring.