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US 2006/0148776 A1Published application
Drug formulations having long and medium chain triglycerides
AssigneeConforma Therapeutics Corporation
InventorsEdqar Ulm, Robert Mansfield, Marcus Boehm
Life of this patent
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Abstract
Drug formulations having emulsifying agents and both medium and long chain triglycerides are described. In preferred embodiments, the long chain triglycerides negate or lessen deleterious central nervous system effects that are caused by medium chain triglycerides.
Claims33
A pharmaceutical composition comprising:
- an HSP90 inhibitor;
- an emulsifying agent;
- and
- an oil, said oil comprising both medium chain triglycerides and long chain triglycerides.
1 more element
A method of lessening the incidence of medium chain triglyceride-mediated central nervous system effects in a patient receiving a drug formulation having medium-chain triglycerides as a component of said formulation, comprising:
- (a) providing a drug formulation comprising an asamycin and both medium and long chain triglycerides, said long chain triglycerides present in an amount sufficient to reduce or negate the incidence of medium-chain fatty acid mediated central nervous system effects ;
- and
- (b) administering the product of step (a) to a patient.
Dependencies are inferred from the claim text.