Composition comprising minocycline as an effective component for prevention and treatment of dementia, and learning and memory impairments
OwnerYoo-Hun Suh, Hye-Sun Kim +3inventors
InventorsYoo-Hun Suh, Hye-Sun Kim, Cheol-Hyoung Park, Eun-Mee Kim, Ki-Young Shin
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Abstract
The present invention relates to a composition for preventing and treating dementia and memory impairment, which contains minocycline as active ingredient. The composition of the present invention has an effect of inhibiting brain cell death and memory impairment, which are induced by amyloid beta-protein and C-terminal protein. Thus, the composition of the present invention is useful for the prevention and treatment of various dementias, including Alzheimer's disease, and the impairment of learning and memory and cognitive function.
Claims12
A method for treating dementia in a patient, comprising administering a therapeutically effective amount of minocycline to a patient in need thereof to inhibit brain cell toxicity of C-terminal protein.
A method for treating memory impairment in a patient, comprising administering a therapeutically effective amount of minocycline to a patient in need thereof to inhibit brain cell toxicity of C-terminal protein.
Dependencies are inferred from the claim text.