Compounds and methods for regulating triglyceride levels
AssigneeMedicure International Inc.
InventorsAlbert Friesen, Marjorie Zettler
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Abstract
The present invention provides a method of administering vitamin B6 related compounds for treatment of hypertriglyceridemia. Vitamin B6 related compounds include pyridoxal, pyridoxal-5′-phosphate, pyridoxamine, a 3-acylated analogue of pyridoxal, a 3-acylated analogue of pyridoxal-4,5-aminal, and mixtures thereof. Embodiments of the present invention also comprise co-administering a lipid lowering agent, such as a nicotinic acid, a fibrate, a HMG CoA reductase inhibitor, a cholesteryl ester transfer protein inhibitor, and combinations thereof.
Claims35
A method of treating hypertriglyceridemia comprising administering a therapeutically effective amount of a vitamin B6 related compound or a pharmaceutically acceptable salt thereof to a patient in need thereof.
A kit comprising:
- (a) a pharmaceutical preparation for administration comprising a compound selected from the group consisting of pyridoxal, pyridoxal-5′-phosphate, pyridoxamine, a 3-acylated analogue of pyridoxal, and a 3-acylated analogue of pyridoxal-4,5-aminal;
- and
- (b) instructions for the administration of said preparation,
- said instructions specifying that said preparation should be administered for the treatment of hypertriglyceridemia.
Dependencies are inferred from the claim text.