Monocyte chemoattractant activity of galectin-3
OwnerFu-Tong Liu, Hideki Sano +1inventors
InventorsFu-Tong Liu, Hideki Sano, Daniel Hsu
Life of this patent
Estimating the term…
Abstract
Inhibitors of galectin-3 expression or activity, for administering to a subject in an amount sufficient to reduce or decrease onset, progression, severity, frequency, duration or probability of one or more symptoms associated with asthma, among other respiratory airway and respiratory mucosal disorders.
Claims54
A method for treating asthma, comprising administering to a subject having or at risk of having an acute or chronic asthmatic episode or an asthma associated symptom, an inhibitor of galectin-3 expression or activity in an amount sufficient to treat asthma.
A method of reducing or decreasing onset, progression, severity, frequency, duration or probability of one or more symptoms associated with asthma, comprising administering to a subject an amount of inhibitor of galectin-3 expression or activity sufficient to reduce or decrease onset, progression, severity, frequency, duration or probability of the one or more symptoms associated with asthma.
47-50. (canceled)
A method for treating a respiratory disorder or a respiratory airway or respiratory mucosal disorder, comprising administering to a subject having or at risk of having an acute or chronic a respiratory disorder or a respiratory airway or respiratory mucosal disorder or an associated symptom, an inhibitor of galectin-3 expression or activity in an amount sufficient to treat the respiratory disorder or the respiratory airway or respiratory mucosal disorder.
52-54. (canceled)
A method of reducing or decreasing the probability, severity, frequency, duration or preventing a subject from having an acute asthmatic episode, comprising administering to a subject that has previously experienced an asthmatic episode or has been diagnosed as having asthma with an amount of an inhibitor of galectin-3 expression or activity sufficient to reduce or decrease onset, probability, severity, frequency, duration or prevent an acute asthmatic episode.
(canceled)
A method of inducing or increasing airway-dilation, comprising administering to a subject in need of increased airway-dilation an amount of an inhibitor of galectin-3 expression or activity sufficient to induce or increase airway-dilation in the subject.
A method of reducing or decreasing probability, severity, frequency, duration or preventing airway-constriction or obstruction, comprising administering to a subject in need of reducing the probability, severity, frequency, duration or preventing airway-constriction or obstruction an amount of an inhibitor of galectin-3 expression or activity sufficient to reduce or decrease the probability, severity, frequency, duration or prevent airway-constriction or obstruction in the subject.
59-89. (canceled)
Dependencies are inferred from the claim text.